Effectiveness of curettage and bone grafting with and without elastic intramedullary nailing in the treatment of simple bone cyst in children: a meta-analysis

刮除术联合植骨术(有或无弹性髓内钉固定)治疗儿童单纯性骨囊肿的疗效:一项荟萃分析

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Abstract

AIM: To systematically evaluate the effectiveness of curettage and bone grafting with and without elastic intramedullary nailing in the treatment of simple bone cyst in children by analyzing domestic and international literature. METHODS: Systematically search for literature comparing the efficacy of curettage and bone grafting with and without elastic intramedullary nailing in the treatment of simple bone cyst in children in databases such as Pubmed, Cochrane Library, Embase, CBM, CNKI, Wanfang, and VIP. Conduct quality assessment and data extraction of included literature and perform meta-analysis calculations using Stata12.0 software. RESULTS: Meta-analysis showed no heterogeneity (P = 0.581, I² = 0%). The cure rate was significantly higher in the EIN group (OR = 2.66, 95% CI = 1.48-4.77, P = 0.001) and 81% lower refracture incidence (OR = 0.19, 95% CI = 0.04-0.87, P = 0.032) vs. curettage alone. CONCLUSION: Curettage and bone grafting with elastic intramedullary nailing is superior to curettage and bone grafting alone for treating simple bone cysts, with lower postoperative refracture incidence. Although the latter may require only one surgery theoretically, refracture or recurrence could necessitate 2-3 additional surgeries.

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