Linear Focal Elastosis: What We Know From Epidemiological Studies

线状局灶性弹力纤维增生症:我们从流行病学研究中了解到的信息

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Abstract

Linear focal elastosis (LFE), characterised by horizontal streaks on the lower back, is a dermatological condition with unclear etiopathogenesis and limited epidemiological data. This study synthesises case reports to elucidate demographic patterns, clinical manifestations, and potential associations. A literature search across PubMed, Embase, Ovid and ResearchGate identified 37 relevant articles, yielding 80 cases after excluding duplicates and irrelevant articles. In analysis, the male-to-female ratio for LFE was 5:1, with a mean age of 39 years. Cases were more common among adolescents and older adults (age ≥ 60), with the majority occurring in pubertal adolescents. No racial predilection was observed. The lower back was the most frequently affected site, with rare cases involving other body parts. Some cases were associated with growth spurts or strenuous exercise, although the etiopathogenesis remains speculative. LFE may be underreported due to its asymptomatic nature and resemblance to other skin conditions, particularly striae distensae. Further research is required to clarify its pathogenesis and explore potential treatment options.

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