Sleep study, respiratory mechanics, chemosensitive response and quality of life in morbidly obese patients undergoing bariatric surgery: a prospective, randomized, controlled trial

接受减肥手术的病态肥胖患者的睡眠研究、呼吸力学、化学敏感性反应和生活质量:一项前瞻性、随机、对照试验

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作者:Luis V F Oliveira, Isabella C Aguiar, Raquel P Hirata, Newton S Faria Junior, Israel S Reis, Luciana M M Sampaio, Claudia S Oliveira, Paulo T C Carvalho, Fernando S S Leitao Filho, Lilian C Giannasi, Lia Azevedo Pinto, Carlos Alberto Malheiros, Wilson Rodrigues Freitas Jr

Background

Obesity is a major public health problem in both developed and developing countries alike and leads to a series of changes in respiratory physiology. There is a strong correlation between obesity and cardiopulmonary sleep disorders. Weight loss among such patients leads to a reduction in these alterations in respiratory physiology, but clinical treatment is not effective for a long period of time. Thus, bariatric surgery is a viable option.

Discussion

This paper describes a randomised controlled trial of morbidly obese patients. Polysomnography, respiratory mechanics, chemosensitive response and quality of life will be assessed in patients undergoing or not undergoing bariatric surgery.

Trial registration

The protocol for this study is registered with the Brazilian Registry of Clinical Trials - ReBEC (RBR-9k9hhv).

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