Invasive Vulval Paget's disease treated with primary radiotherapy: A rare case report and literature review

采用原发性放射治疗治疗侵袭性外阴佩吉特病:一例罕见病例报告及文献综述

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Abstract

Extramammary Vulval Paget's Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety. Among invasive Paget's disease, only 20% cases show invasion more than 1 mm. The present report describes a unique case of an invasive extra-mammary VPD with depth of invasion more than 4 mm presenting at a relatively young perimenopausal lady. Only 14 cases of VPD has been treated with primary radiotherapy in literature till date. We report this case to be the 15th case where radiotherapy was solely used to treat an invasive VPD.

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