Abstract
•Superior mesenteric vein thrombosis (SMVT) is rare but seen in patients with hypercoagulable states.•Prevention of mortality in patients with SMVT requires immediate diagnosis and complex management.•A hierarchical approach to treatment progresses to more aggressive treatment as needed.•Supportive care, medication, and endovascular and/or surgical interventions are available management options.•In patients with underlying conditions, long-term treatment such as anticoagulation must also be initiated.