Endometrial stromal nodule of the vaginal wall with a review of vulvovaginal endometrial stromal neoplasms

•It is reported the first endometrial stromal nodule (ESN) in the vagina.•This is an excepcionall ESN because it was not associated with endometriosis•It was successfully treated by local resection.•Primary vulvovaginal endometrial stromal neoplasms are rare (only 5 reported).