Estimating VO(2peak) in 18-90 Year-Old Adults: Development and Validation of the FitMáx©-Questionnaire

评估 18-90 岁成年人的 VO₂peak:FitMáx© 问卷的开发和验证

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Abstract

PURPOSE: Cardiorespiratory fitness (CRF) plays an essential role in health outcomes and quality of life. However, it is often not assessed nor estimated. Objective CRF assessment is costly, labour intensive and not widely available. Patient-reported outcome measures estimate CRF more cost-efficiently, but current questionnaires lack accuracy. The aim of this study is to develop a new self-reported questionnaire to estimate CRF. MATERIALS AND METHODS: The FitMáx©-questionnaire, consisting of only three questions assessing walking, stair climbing, and cycling capacity, was compared with the commonly used Duke Activity Status Index (DASI) and Veterans Specific Activity Questionnaire (VSAQ). These questionnaires were compared to peak oxygen uptake (VO(2peak)) as measured with cardiopulmonary exercise testing. This study included 759 cardiac, pulmonary and oncologic patients and healthy persons aged 18‒90. RESULTS: FitMáx© strongly correlated (r = 0.94 (0.92‒0.95) SEE = 4.14 mL∙kg(-1)∙min(-1)) with measured VO(2peak). Bias between predicted and measured VO(2peak) was -0.24 (-9.23‒8.75; 95% limits of agreement) mL·kg(-1)·min(-1). The FitMáx© scored superiorly on correlation and SEE compared with the DASI and VSAQ, r = 0.75 (0.68‒0.80) SEE = 4.62 mL∙kg(-1)∙min(-1) and r = 0.87 (0.83‒0.90) SEE = 6.75 mL∙kg(-1)∙min(-1), respectively. CONCLUSION: FitMáx© is a valid and accessible questionnaire to estimate CRF expressed as VO(2peak) in clinical practice and shows substantial improvement compared to currently used questionnaires.

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