Simultaneous Determination of Glucose and Cholesterol in Milk Samples by Means of a Screen-Printed Biosensor and Artificial Neural Networks

利用丝网印刷生物传感器和人工神经网络同时测定牛奶样品中的葡萄糖和胆固醇

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Abstract

In the present work, a bienzymatic voltammetric biosensor is reported for the simultaneous quantification of glucose and cholesterol in flavored milk samples with a single device. The biosensor is based on a carbon screen printing electrode on which paper disks impregnated with glucose oxidase and cholesterol oxidase, as well as ferricyanide as a mediator, are deposited. Linear voltammetry combined with an artificial neural network methodology were successfully used for the determinations, showing excellent agreement with the spectrophotometric reference method.

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