An alternative solution for patient with high risk of coronary obstruction underwent TAVI procedure using a novel second-generation device - a case series

对于冠状动脉阻塞高风险患者,采用新型第二代经导管主动脉瓣置换术(TAVI)提供了一种替代方案——病例系列研究

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Abstract

BACKGROUND: Obstruction of the left or right coronary artery is a rare but lethal complication during transcatheter aortic valve implantation (TAVI). The new J-Valve™ prosthesis is a new second generation TAVI device which has several features to avoid the coronary obstruction such as low profile design and clip fixation of the native leaflets. The aim of this study is to report our initial experience of using this valve in treating patient with high risk factors for coronary obstruction during TAVI procedure. CASE PRESENTATION: Three high surgical risk patients (All females with 77, 76, and 75 years old) with symptomatic aortic stenosis were enrolled. All patients have the common feature of low coronary ostium height (< 10 mm) with narrowed aortic sinus (< 30 mm) on CT angiogram and marked leaflet calcification. Three 25 mm J-Valve prostheses were successfully implanted through trans-apical approach. No coronary obstruction was noted for these patients. Effective aortic open area was significantly increased after valve implantation (Preoperative 0.7, 0.7 and 0.65 cm(2) - Postoperative 1.8, 1.9 and 2.0 cm(2)). Only one patient was noted to have trivial degree paravalvular leakage. CONCLUSION: The new J-Valve prosthesis is a new second generation TAVI device. This system may provide another safety treatment option for patient with high risk factor for coronary obstruction underwent TAVI procedure.

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