Abstract
ObjectivesNumerous studies have demonstrated the safety and efficacy of percutaneous MitraClip transcatheter interventional therapy in treating mitral regurgitation. This study reports the largest series of outcomes in Vietnamese patients who underwent the MitraClip procedure.Methods and resultsBetween September 2014 and December 2024, 23 patients (20 males and 3 females; mean age, 66.3 ± 10.2 years) underwent the MitraClip procedure at five hospitals across Vietnam. Key findings included a high procedural success rate, with 91.3% of patients receiving successful implantations. Postprocedural complications were observed in 33.3% of patients. During the 30-day follow-up, two patients (9.5%) were readmitted; however, no mortality was reported. All patients achieved a mitral regurgitation grade of ≤2+, and 92.9% showed improvement to New York Heart Association Class I/II within 30 days postprocedure.ConclusionsMulticenter data from hospitals across Vietnam indicate that the MitraClip procedure is effective in reducing mitral regurgitation and demonstrate favorable short-term safety outcomes.