Abstract
INTRODUCTION: Chronic smoking is still one of the world's leading health problems. In addition to the systemic effects of cigarette smoking, ocular effects are also present, as ocular structures are a mucosal surface. The aim of this study was to investigate the effects of chronic cigarette smoking on the anterior segment and pupil using Sirius corneal topography. MATERIALS AND METHODS: The study included 70 chronic smokers in the experimental group and 72 non-smokers in the control group. Central corneal thickness (CCT); corneal volume (CV); anterior chamber depth (ACD); anterior chamber angle (ACA); anterior chamber volume (ACV); first non-contact tear breakup time (NCTBUT); mean NCTBUT; meibography; scotopic, mesopic and photopic pupil sizes; and dynamic pupil sizes at 0, 1, 2, 4, 6, 8 and 10 s were measured. RESULTS: There were no statistically significant differences between the chronic smoker group and the control group in terms of age; gender; CCT; CV; ACD; ACA; ACV; first NCTBUT; mean NCTBUT; and dynamic pupillometry at 2, 4, 6, 8 and 10 s. There were statistically significant differences between the groups in terms of meibography; scotopic, mesopic and photopic static pupillometry; and dynamic pupillometry at 0 and 1 s. CONCLUSION: In this study, only the meibomian gland was affected among the anterior segment structures. Changes in other anterior segment structures were not significant. On the pupil, chronic smoking increased the scotopic, mesopic and photopic pupil diameter and the early stages of dynamic pupillometry. In addition CV; ACD; ACA; ACV; first NCTBUT; mean NCTBUT; and dynamic pupillometry are important in terms of being the first literature in which they were evaluated.