Down regulation of fatty acid synthase via inhibition of PI3K/AKT/mTOR in ovarian cancer cell line by novel organoselenium pseudopeptide
新型有机硒伪肽通过抑制卵巢癌细胞系中的 PI3K/AKT/mTOR 来下调脂肪酸合酶
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作者：Abeer M El-Saudi, Miram A Altouhamy, Saad Shaaban, Farid A Badria, Magdy M Youssef, Fardous F El-Senduny
Conclusion
This work highlights the unique role of Compound 4 against OC via modulation of oxidative stress, inhibition of survival PI3K/AKT/mTOR pathway. Compound 4 was found to be a promising alternative therapy for the treatment of OC in this investigation.
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