Phenotype and biological characteristics of endometrial mesenchymal stem/stromal cells: A comparison between intrauterine adhesion patients and healthy women

子宫内膜间充质干/基质细胞的表型和生物学特性:宫腔粘连患者与健康妇女的比较

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作者:Jiali Min, Na Lu, Shengjian Huang, Xiahua Chai, Susu Wang, Lin Peng, Jian Wang

Conclusion

There are some differences between the EMSCs of IUA patients and healthy women, which may be related to the occurrence of IUA and dysfunction of endometrium.

Results

Our results showed that there were fewer CD146+ CD140b+ cells in patients with IUA, and the clone-forming, migration, invasion, angiogenic and immunosuppressive abilities of the EMSCs of patients with IUA were significantly decreased compared with those of healthy women.

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