Abstract
INTRODUCTION AND SIGNIFICANCE: Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a rare renal tumor primarily associated with female patients and those with tuberous sclerosis complex (TSC). Despite lacking distinct clinical or radiological features, its unique histological characteristics allow for differentiation from other renal neoplasms. While it often exhibits indolent growth, metastatic potential remains a concern. Surgical resection with pathological confirmation is the standard of care. CASE PRESENTATION: We present a case of a patient who presented with mild flank pain. Successful treatment was achieved, followed by a 12-month uneventful follow-up. CLINICAL DISCUSSION: ESC RCC typically demonstrates a favorable prognosis, often detected at an early stage. However, complete surgical resection with adjunct imaging is recommended to rule out metastatic disease. Despite its indolent nature, a vigilant approach is warranted due to the potential for incomplete tumor visualization. CONCLUSION: This case report contributes to the growing body of literature on ESC RCC. By documenting our experience and reviewing the existing literature, we aim to enhance our understanding of this rare entity and optimize patient care.