Meckel's diverticulum with ectopic pancreatic and epididymal tissue in a newborn infant

新生儿梅克尔憩室伴异位胰腺和附睾组织

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Abstract

INTRODUCTION AND IMPORTANCE: Meckel's diverticulum is a congenital anomaly affecting about 2 % of the population due to incomplete omphalomesenteric duct closure during fetal development. While often asymptomatic, it can cause complications like obstruction and bleeding. Ectopic tissue within the diverticulum, such as gastric and pancreatic tissue, is reported. This report presents a unique case of ectopic pancreatic and epididymal tissue in a newborn's Meckel's diverticulum, emphasizing the significance of histopathological examination. CASE PRESENTATION: A term male newborn presented with abdominal distension and bilious vomiting shortly after birth. Physical examination revealed a palpable abdominal mass. Ultrasound showed a dilated bowel loop with a blind-ending tubular structure suggestive of Meckel's diverticulum. Surgical resection identified a diverticulum 30 cm from the ileocecal valve. Histological examination confirmed ectopic pancreatic and epididymal tissue within the diverticulum. CLINICAL DISCUSSION: The coexistence of ectopic pancreatic and epididymal tissue in Meckel's diverticulum is extremely rare. The embryological mechanism remains unclear, likely involving aberrant cell differentiation. Differential diagnosis in neonates with similar symptoms includes volvulus and Hirschsprung's disease. Imaging and histopathology are crucial for diagnosis. This case underscores the diverse ectopic tissue potential in Meckel's diverticulum and the importance of thorough evaluation. CONCLUSION: Ectopic tissue in Meckel's diverticulum should be considered in differential diagnoses of neonatal abdominal obstruction. Awareness and timely surgical intervention are vital for management.

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