Warthin-like variant of Papillary thyroid carcinoma-Case report of an uncommon tumour with review of literature

乳头状甲状腺癌的沃辛样变异型——罕见肿瘤病例报告及文献复习

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Abstract

BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis. CASE REPORT: A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II - level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well. CONCLUSION: Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management.

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