Human-specific subcellular compartmentalization of P-element induced wimpy testis-like (PIWIL) granules during germ cell development and spermatogenesis
在生殖细胞发育和精子发生过程中,P 元素诱导的弱睾丸样 (PIWIL) 颗粒的人类特异性亚细胞区室化
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作者:Maria Gomes Fernandes, Nannan He, Fang Wang, Liesbeth Van Iperen, Cristina Eguizabal, Roberto Matorras, Bernard A J Roelen, Susana M Chuva De Sousa Lopes
| 期刊: | Human Reproduction | 影响因子: | 6.000 |
| 时间: | 2018 | 起止号: | 2018 Feb 1;33(2):258-269. |
| doi: | 10.1093/humrep/dex365 | 种属: | Human |
| 研究方向: | 细胞生物学 | 细胞类型: | 其它细胞 |
Methods
Human fetal gonads from elective abortion without medical indication and adult testes biopsies were donated for research with informed consent. Samples were fixed, paraffin-embedded and analyzed by immunofluorescence to study the temporal and cellular localization of PIWIL1, PIWIL2, PIWIL3 and PIWIL4. Main
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