Abstract
INTRODUCTION: Infantile hemangioma is the most common tumor in infancy, with 60% occurring on the face and neck. A large tumor involving the facial region will cause significant aesthetic and functional impairment and isn't always easy to treat surgically. A non-invasive treatment is needed for this condition. Propranolol has recently been used as a choice of treatment in infantile hemangioma. PRESENTATION OF CASE: We presented two cases of large problematic infantile hemangioma that were successfully managed with oral propranolol. DISCUSSION: Large problematic lesions that ulcerate and bleed often need surgery; however, a substantial defect resulting from surgery is tricky to reconstruct and can cause significant scar. Propranolol is used because of its efficacy and low risk characteristics. CONCLUSION: Propranolol is an effective treatment to reduce the need of surgical intervention in problematic hemangioma.