Abstract
Myolipoma is a rare benign lipomatous soft tissue neoplasm, occurring most frequently in adults in the abdomen, pelvis or retroperitoneum. We presented a case of a 39-year-old female with an epipleural lesion at the left paraspinal region identified using computed tomography. Magnetic resonance imaging revealed a fat-containing lesion attached to the pleura over the left paraspinal region. Surgical resection was performed, and histopathological analysis revealed a tumour composed of interlacing bundles of neoplastic smooth muscle cells with low cellularity and rare mitotic figures intermixing with mature adipocytes. The presence of oestrogen and progesterone receptors in smooth muscle cells was noted. The mass was reported as myolipoma. To the best of our knowledge, this case is the first description of an intrathoracic myolipoma.