Abstract
OBJECTIVE: This study aimed to investigate the potential factors influencing the early efficacy outcomes of patients with acute ischaemic stroke (AIS) after endovascular interventional therapy. METHODS: A retrospective analysis was conducted involving 326 patients with AIS. The early efficacy outcomes and complications among patients after emergency cerebrovascular intervention were evaluated. Univariate analysis was performed to compare the baseline data between good outcome and poor outcome groups. Binary logistic regression analysis was used to determine the independent risk factors for poor outcomes at discharge. RESULTS: Among the 326 patients, 174 (53.4%) had poor outcomes at discharge. Univariate analysis showed that a poor prognosis was associated with age, history of atrial fibrillation and stroke, a high preoperative National Institutes of Health Stroke Scale (NIHSS) score, a low thrombolysis in cerebral infarction (TICI) grade after thrombectomy, and a high incidence of postoperative symptomatic intracranial haemorrhage and cerebral oedema/hernia (P < 0.05). Binary logistic regression analysis showed that age (P = 0.010), NIHSS score before surgery (P < 0.001), the Alberta Stroke Program Early CT Score (ASPECTS) before surgery (P < 0.001), TICI grade after thrombectomy (P < 0.001), symptomatic intracranial haemorrhage after surgery (P = 0.001) and cerebral oedema/hernia after surgery (P = 0.004) were independent risk factors for a poor outcome at discharge. CONCLUSION: Age, NIHSS score before surgery, ASPECTS before surgery, TICI grade after thrombectomy, symptomatic intracranial haemorrhage, and cerebral oedema/hernia after surgery were independent risk factors for poor short-term outcomes after endovascular interventional therapy for AIS.