Regulation of mechanosensitive biliary epithelial transport by the epithelial Na(+) channel

上皮细胞Na+通道对胆管上皮细胞机械敏感性转运的调节

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作者:Qin Li, Charles Kresge, Abhijit Bugde, Michelle Lamphere, Jason Y Park, Andrew P Feranchak

Conclusion

These studies represent the initial characterization of mechanosensitive Na(+) currents activated by flow in biliary epithelium; understanding the role of mechanosensitive transport pathways may provide strategies to modulate the volume and composition of bile during cholestatic conditions. (Hepatology 2016;63:538-549).

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