Data on the expression and role of TREM-1 in the development of in-stent restenosis

TREM-1 在支架内再狭窄发展中的表达和作用的数据

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作者:Fang Wang, Chang Li, Feng Hua Ding, Ying Shen, Jie Gao, Zhu Hui Liu, Jia Wei Chen, Rui Yan Zhang, Wei Feng Shen, Xiao Qun Wang, Lin Lu

Abstract

The data presented in this article are related to the research article entitled "Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells" (Wang et al., 2017) [1], which demonstrated that TREM-1 is expressed on vascular smooth cells (VSMCs) and promotes inflammation, proliferation and migration in cultured VSMCs. In this dataset, the expression of TREM-1 in leukocytes and endothelial cells of carotid artery after ligation was evaluated. The effect of TREM-1 on stenosis was analyzed in cultured human saphenous veins (HSVs) that spontaneously undergo remodeling which involves VSMC proliferation and migration.

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