Abstract
A 29-year-old man with severe haemophilia A developed right lower quadrant pain. He was diagnosed with jejuno-jejunal intussusception, and he was managed conservatively with an infusion of plasmatic factor VIII, resulting in resolution of symptoms, and reduction of the jejuno-jejunal intussusception, and complete regression of hematoma. This case highlights a rare clinical manifestation in patients with haemophilia, and also indicates the effectiveness of factor VIII instead of exploratory surgery for intramural hematoma.