Case Report: (18)F-Fluorocholine PET/CT for detecting brown tumours in patients with hyperparathyroidism: a short case series and literature review

病例报告:(18)F-氟代胆碱PET/CT在甲状旁腺功能亢进患者棕色瘤检测中的应用:简短病例系列及文献综述

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Abstract

INTRODUCTION: Brown tumours (BTs), also known as osteitis fibrosa cystica, are benign osteolytic lesions associated with hyperparathyroidism (HPT). BTs are cured by correcting the hypercalcaemia and HPT, which often requires surgical resection of the parathyroid adenoma. (1)⁸F-fluorocholine (FCH) PET/CT is becoming an effective tool for detecting parathyroid adenomas in cases of hyperparathyroidism. This study aims to evaluate the role of FCH PET/CT in detecting brown tumours in patients with hyperparathyroidism. CLINICAL CASES: Three cases are presented to demonstrate the effectiveness of FCH PET/CT in detecting BTs in patients presenting with clinical and biochemical signs of HPT with suspicion of BTs. LITERATURE REVIEW: A literature review aimed to summarize the bibliographic evidence on the use of this technique in this setting, which is relatively innovative. CONCLUSION: FCH PET/CT appears to be a useful tool for detecting BTs, and further prospective studies are needed to confirm this.

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