Abstract
The recently published 4th International Consensus Guidelines on the Management of CMV in Solid-Organ Transplantation offers updated recommendations for CMV prevention, treatment, and monitoring in pediatric solid organ transplant (pSOT) recipients. Although these guidelines are supported by a thorough review of published data, there remain unanswered questions due to a paucity of pediatric data, conflicting findings across studies, or areas where pediatric and adult data are divergent. The current report highlights controversial areas of management, emphasizes the rationale for certain expert opinions, and calls attention to topics that require further research using a case-based approach.