Neurotoxic manifestations of an overdose intrathecal injection of gadopentetate dimeglumine

鞘内注射过量钆喷酸葡胺引起的神经毒性表现

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Abstract

The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global aphasia, rigidity, and visual disturbance.

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