The mechanism by which ATP regulates alcoholic steatohepatitis through P2X4 and CD39
ATP通过P2X4和CD39调控酒精性脂肪性肝炎的机制
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作者：Guo-Qing Xia, Jun-Nan Cai, Xue Wu, Qian Fang, Ning Zhao, Xiong-Wen Lv
Conclusion
These results suggest that the ATP-P2X4 signaling pathway promotes the inflammatory response in alcoholic steatohepatitis and that CD39 may play a protective role in regulating P2X4 expression by hydrolyzing ATP. In conclusion, the CD39 and ATP-P2X4 signaling pathways may be potential therapeutic targets for alcoholic steatohepatitis.
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