Synthesis of dual-phase Ti(3)O(5)/Ti(4)O(7) nanofibers for efficient adsorption of SARS-CoV-2

合成双相Ti(3)O(5)/Ti(4)O(7)纳米纤维用于高效吸附SARS-CoV-2

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Abstract

In this study, we synthesized the dual-phase Ti(3)O(5)/Ti(4)O(7) nanofibers for efficient adsorption of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a life-threatening virus being taking millions of people lives. The Ti(3)O(5)/Ti(4)O(7) nanofibers were synthesized by preparation of H(2)Ti(3)O(7) precursor, polydopamine coating and furnace calcination. Protein and phospholipid adsorption assays showed that the dual-phase nanofibers had much higher affinity to both the model molecules bovine serum album (BSA) and phosphatidylethanolamine (PE) than the control single-phase Ti(6)O(11) nanofibers. Consistently, the dual-phase nanofibers exhibited much stronger adsorption ability to SARS-CoV-2 pseudovirus than Ti(6)O(11). This study sheds a light on titanium oxide nanomaterials to adsorb SARS-CoV-2 for avoiding its infection and for capturing it during rapid virus detection.

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