Abstract
Dirofilariasis is a zoonotic infection that humans acquire by the bite of infected mosquitoes. The male reproductive system is relatively rare affected by this disease. We presented a case of dirofilariasis of the scrotum from Bulgaria. The patient noticed a small painless nodule in his scrotum with no other pathological findings. The tumor-like lesion was surgically removed. Dirofilariasis was not suspected before this procedure, but the diagnosis was made on histological examination of the extracted tissue. Surgical removal of the helminth is the radical treatment of this disease. Dirofilariasis of the scrotum has a good prognosis as patients fully recover after the extraction of the parasite.