Abstract
PURPOSE: To compare four free-breathing scan techniques for gadoxetic acid-enhanced hepatobiliary phase imaging with conventional breath-hold scans. MATERIALS AND METHODS: Gadoxetic acid-enhanced hepatobiliary phase imaging with six image acquisition sets performed in 50 patients. Image acquisition sets included fat-suppressed 3D T(1)-weighted turbo field echo with free-breathing pseudo-golden-angle radial stack-of-stars (FBRS) acquisition, FBRS with track (FBRS(T)), FBRS with gate and track (FBRS(G&T)), thin-slice FBRS with gate and track (thin-slice FBRS(G&T)), free-breathing Cartesian acquisition (Cartesian(FB)), and breath-hold Cartesian acquisition (Cartesian(BH)). Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and image quality compared to the six-image acquisition sets. RESULTS: Signal-to-noise ratio and CNR were significantly higher in FBRS, FBRS(T), FBRS(G&T), and thin-slice FBRS(G&T) than in Cartesian(FB) and Cartesian(BH) (P < 0.001). Based on sharpness, motion artifacts, visibility of intrahepatic vessels, and overall image quality, thin-slice FBRS(G&T) had the highest image quality followed by Cartesian(BH) and FBRS(G&T) (P < 0.001). Severe motion artifacts were observed in 25 patients in Cartesian(FB) and three patients in Cartesian(BH), whereas image quality remained above the acceptable range in FBRS(G&T), FBRS(T), FBRS, and thin-slice FBRS(G&T) in all cases. CONCLUSION: Thin-slice FBRS(G&T) demonstrated excellent image quality compared with conventional Cartesian(BH) in gadoxetic acid-enhanced hepatobiliary phase imaging. It can be apply to supplemental sequences of patients with unstable breath holding.