Abstract
BACKGROUND: This study aimed to evaluate the effects of nursing quality control combined with intensified psychological care on negative emotions and health outcomes in patients undergoing blood purification. METHODS: Patients who underwent blood purification at the Affiliated Hospital of Jiangnan University (China) from January 2021 to December 2023 were enrolled and assigned to either a control or an intervention group using a random number table. Both groups received standard care, while the intervention group additionally received nursing quality control and intensified psychological care. Outcomes compared between groups included negative emotions (assessed by the Hamilton Anxiety Scale and Hamilton Depression Scale scores), quality of life (SF-36), treatment adherence, and complication rates. RESULTS: Prior to the treatment, both groups (150 patients in each) were comparable in the Hamilton Anxiety Scale, the Hamilton Depression Scale, and SF-36 scores. After the treatment, the intervention group showed significantly greater reduction in the Hamilton Anxiety Scale (15.89 vs. 7.19) and Hamilton Depression Scale (12.22 vs. 4.74) scores, and greater improvements in SF-36 scores, particularly in physical functioning (37.99 vs. 22.61) and mental health (34.48 vs. 18.95). Moreover, treatment adherence was significantly higher in the intervention group (98.67% vs 70%), while the complication rate was markedly lower (10% vs. 35.33%). All differences were statistically significant (p < 0.001). CONCLUSIONS: Nursing quality control combined with intensified psychological care significantly improves negative emotional states and quality of life in patients undergoing blood purification, while also enhancing treatment adherence and reducing the incidence of complications.