Background
Hepatocellular carcinoma (HCC) is a primary liver cancer with a high mortality rate. However, the molecular mechanism of HCC formation remains to be explored and studied.
Methods
The data set of hepatocellular carcinoma was downloaded from GEO database for differential gene analysis, and hub gene was identified by Cytoscape. GEPIA was used to verify the expression of HUB gene and evaluate its prognostic value. Then TOP2A was selected as the research object of this paper by combining literature and clinical sample
Objective
To investigate the expression of TOP2A in hepatocellular carcinoma (HCC) and its prognosis.
Results
TOP2A may be a new biomarker and therapeutic target for hepatocellular carcinoma.