Abstract
•Site-specific administration is key for optimizing anticancer drug administration; self-healing hydrogels may allow this at reasonable costs and reproducibility.•Self-healing hydrogels have several real-world therapeutic applications, including drug administration.•Self-healing hydrogels are yet to be utilized for chemotherapy drug administration in clinical trials.•Clinical research on using self-healing hydrogels in anticancer therapeutics is feasible and valid compared to other advances in anticancer drug administration.