Optimizing statistical evaluation of multiclass classification in diagnostic radiology: a study of the two-parameter multidimensional nominal response model

优化诊断放射学中多分类的统计评估:双参数多维名义响应模型的研究

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Abstract

PURPOSE: This study aimed to enhance the multidimensional nominal response model (MDNRM) for multiclass classification in diagnostic radiology. MATERIALS AND METHODS: This retrospective study involved the extension of the conventional nominal response model (NRM) to create the two-parameter MDNRM (2PL-MDNRM). Seven models of MDNRM, including the original MDNRM and subtypes of 2PL-MDNRM, were employed to estimate test-takers' abilities and test item complexity. These models were applied to a clinical diagnostic radiology dataset. Rhat values were calculated to evaluate model convergence. Additionally, values of the widely applicable information criterion (wAIC) and Pareto-smoothed importance sampling leave-one-out cross-validation (LOO) were calculated to evaluate the goodness of fit of the seven models. The best-performing model was selected based on the values of wAIC and LOO. Probability of direction (PD) was used to evaluate whether one estimated parameter significantly differed. RESULTS: All estimated parameters across the seven models demonstrated Rhat values below 1.10, indicating stable convergence. The best wAIC and LOO values (988 and 1,121, respectively) were achieved with 2PL-MDNRM (r) using the truncated normal distribution and 2PL-MDNRM (a) using the truncated normal distribution. Notably, one test-taker (radiologist) exhibited significantly superior ability compared to another based on PD results from the best models, while no significant difference was observed in nonoptimal models. CONCLUSION: 2PL-MDNRM successfully achieved parameter estimation convergence, and its superiority over the original MDNRM was demonstrated through wAIC and LOO values.

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