Lung adenocarcinoma patient progression with gastrointestinal metastasis response to subsequent tyrosine kinase inhibitors (TKIs) from re-biopsy of new occurring driver gene mutation

肺腺癌患者出现胃肠道转移，经再次活检发现新的驱动基因突变后，对后续酪氨酸激酶抑制剂（TKI）治疗反应不佳。