Abstract
PURPOSE: Endocrinology and Metabolism Research Institute (EMRI), Tehran University of Medical Sciences, has achieved many advances in the understanding of epidemiology, pathology, and molecular biology of thyroid cancer (TC). This paper will focus on published literature in the field of TC research at EMRI since its inception. METHODS: A comprehensive literature search of "Scopus", "Web of Science (ISI)", "PubMed", and "SID" databases was done to identify TC-based studies in EMRI since 2005, using the predefined keywords. RESULTS: All the records were reviewed. Eventually, 46 articles that met the inclusion and exclusion criteria were considered. Timeline, characteristics, and summarized findings of the included most studies have been briefly described. CONCLUSION: The main focus of the TC research at EMRI is to investigate genetic and epigenetic changes as well as the cellular and molecular aspects seen more frequently in TC patients, and find out how exactly these alterations lead to more aggressive TC behavior and resistance to the conventional treatment approaches in those patients.