Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis(1)

COVID-19 相关肺曲霉病的多国观察性队列研究(1)

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作者：Janssen,Nico A F,Nyga,Rémy,Vanderbeke,Lore,Jacobs,Cato,Ergün,Mehmet,Buil,Jochem B,van Dijk,Karin,Altenburg,Josje,Bouman,Catherine S C,van der Spoel,Hans I,Rijnders,Bart J A,Dunbar,Albert,Schouten,Jeroen A,Lagrou,Katrien,Bourgeois,Marc,Reynders,Marijke,van Regenmortel,Niels,Rutsaert,Lynn,Lormans,Piet,Feys,Simon,Debavaye,Yves,Tamion,Fabienne,Costa,Damien,Maizel,Julien,Dupont,Hervé,Chouaki,Taieb,Nseir,Saad,Sendid,Boualem,Brüggemann,Roger J M,van de Veerdonk,Frank L,Wauters,Joost,Verweij,Paul E
期刊：Emerging Infectious Diseases影响因子：6.600
时间：2021起止号：2021 Nov;27(11):2892-2898
doi：10.3201/eid2711.211174

Abstract

We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease-associated pulmonary aspergillosis (CAPA). We found 10%-15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%-52%.

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