Spectroscopic and crystallographic characterization of two cathinone derivatives: 1-(4-fluorophenyl)-2-(methylamino)pentan-1-one (4-FPD) hydrochloride and 1-(4-methylphenyl)-2-(ethylamino)pentan-1-one (4-MEAP) hydrochloride

两种卡西酮衍生物的光谱和晶体学表征:1-(4-氟苯基)-2-(甲氨基)戊-1-酮 (4-FPD) 盐酸盐和 1-(4-甲基苯基)-2-(乙氨基)戊-1-酮 (4-MEAP) 盐酸盐

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作者:Marcin Rojkiewicz, Piotr Kuś, Joachim Kusz, Maria Książek

Conclusions

Dynamic growth in the number of psychoactive substances available on the designer drug markets makes it compulsory to obtain analytical data allowing unequivocal identification of these drugs in the fastest possible way. In this study we presented analytical data useful in quick identification of the investigated compounds.

Methods

The compounds were characterized by electrospray ionization ion trap mass spectrometry (MS) in MS2 and MS3 modes, gas chromatography-MS, infrared, Raman and ultraviolet-visible spectroscopies, X-ray crystallography, differential scanning calorimetry and nuclear magnetic resonance spectroscopy.

Purpose

In this study, we performed identification and physicochemical characterization of two cathinone derivatives, 4-FPD and 4-MEAP, found in market-available materials.

Results

We could obtain detailed and comprehensive physicochemical characterization of 4-FPD and 4-MEAP-new cathinone derivatives available on the designer drugs market. Conclusions: Dynamic growth in the number of psychoactive substances available on the designer drug markets makes it compulsory to obtain analytical data allowing unequivocal identification of these drugs in the fastest possible way. In this study we presented analytical data useful in quick identification of the investigated compounds.

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