Electrochemical B-H Nitrogenation: Access to Amino Acid and BODIPY-Labeled nido-Carboranes

电化学BH氮化:获得氨基酸和BODIPY标记的巢式碳硼烷

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Abstract

Electrocatalyzed oxidative B-H nitrogenations of nido-carborane (nido-7,8-C(2) B(9) H(12)(-) ) with N-heterocycles have been established, enabling the preparation of various N-substituted nido-carboranes without chemical oxidants or metal catalyst under ambient conditions. The electrolysis manifold occurred with high levels of efficiency as well as chemo- and position- selectivity, employing sustainable electricity as the sole oxidant. The strategy set the stage for a user-friendly access to novel amino acid and fluorogenic boron-dipyrrin (BODIPY)-labeled nido-carborane hybrids.

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