Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations

吲哚环化反应衍生的铑(I)卡宾的差异性反应活性

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Abstract

Rhodium(I) carbenes were generated from propargylic alcohol derivatives as the result of a dehydrative indole annulation. Depending on the choice of the electron-withdrawing group on the aniline nitrogen nucleophile, either a cyclopropanation product or dimerization product was obtained chemoselectively. Intramolecular hydroamidation occurred for the same type of propargylic alcohol derivatives when other transition-metal catalysts were employed.

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