Conclusions
We found indications that endothelial dysfunction plays a role in chronic CRPS.
Methods
We performed immunohistochemical staining on sections of skin specimens obtained from the amputated limbs (one arm and one leg) of two patients with CRPS.
Results
In comparison to proximal specimens we found an increased number of migrated endothelial cells as well as an increase of eNOS activity in distal dermis specimens. Conclusions: We found indications that endothelial dysfunction plays a role in chronic CRPS.