Abstract
Hepatic mucinous cystic neoplasms (MCN) are rare cystic tumors that are predominantly observed in females, with a low incidence rate in males. To date, few cases of aggressive MCN have been reported in male patients. The current study reports the case of a 74-year-old male patient who presented to Xixi Hospital with abdominal distension. Results of imaging investigations revealed a cystic lesion in the liver and histopathological examination demonstrated positive staining for caudal type homeobox 2, cytokeratin 20, postmeiotic segregation increased 2, progesterone receptor and α-inhibin, leading to a definitive diagnosis of hepatic mucinous cystadenoma. Collectively, the results of the present article demonstrated that hepatic MCN should be considered in the differential diagnosis of cystic liver lesions, including in male patients. A comprehensive evaluation that integrates clinical characteristics, and imaging and histopathological findings is essential for the optimal management of this condition.