Abstract
The present study reports on the usefulness of FlowGate(2) (FG2) as a novel balloon guide catheter (BGC) for mechanical thrombectomy (MT) treatment. MT using a BGC device was performed on 255 patients at the authors' institution (St. Vincent's hospital, Suwon, Korea and Hangang Sacred Heart Hospital, Seoul, Korea) between January 2014 and September 2018. A total of 235 patients underwent successful application of BGCs and were divided into two groups; an FG2 and a Merci group, and a comparative analysis was performed. The failure rate in the FG2 group (2.5%) was significantly lower than that in the Merci group (10.8%; P=0.016). Occurrence of distal emboli was significantly lower in the FG2 group (4.7%) than in the Merci group (7.3%; P=0.012). According to subgroup analysis of the BGC and the intermediate catheter, the incidence rate of the distal emboli in the FG2 with an intermediate catheter (2.3%) was significantly lower than that of the Merci with an intermediate catheter (6.6%; P=0.038). The ratio of thrombolysis in cerebral infarction (TICI) 3 recanalization in the first pass was higher in the FG2 group than in the Merci group, in both total (44.7 vs. 34.7%; P=0.033) and subgroup patients (46.5 vs. 34.4%; P=0.029). In the multivariate analysis, use of an intermediate catheter [odds ratio (OR), 0.75; 95% confidence interval (CI), 0.66-0.94; P=0.029] and FG2 application (OR, 0.59; 95% CI, 0.25-0.93; P=0.020) were the predictive factors for fewer distal emboli. In summary, FG2 BGC enables an effective MT with less application failures and occurrence of distal emboli, and higher TICI 3 recanalization at the first stent passage, compared with Merci BGC.