Abstract
This is the first ever reported case of mpox (monkeypox) causing penile lesions and acute urinary retention (AUR) in a homosexual man, who had intercourse with his confirmed positive mpox (monkeypox) partner. The patient did not have any significant comorbidities and was managed conservatively with an urgent urethral catheter and co-amoxiclav as per the microbiologist's advice to cover for his skin soft tissue infection (SSI). His blood parameters, urine and blood cultures were all normal. He was successfully trialled without a catheter (TWOCd) in a few days and was discharged home with an outpatient follow-up plan in Andrology Clinic with a flow rate, postvoid residual (PVR), International Prostate Symptoms Score (IPSS) and pain score. He was also planned to be contacted by the sexual health team to ensure a holistic follow-up.