Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rv not predicted by genomics

蛋白质组学揭示了结核分枝杆菌H37Rv中基因组学未预测到的开放阅读框

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Abstract

Genomics revealed the sequence of 3924 genes of the H37Rv strain of Mycobacterium tuberculosis. Proteomics complements genomics in showing which genes are really expressed, and here we show the expression of six genes not predicted by genomics, as proved by two-dimensional electrophoresis and matrix-assisted laser desorption ionization and nano-electrospray mass spectrometry.

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