Identification of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan

日本鸡肉中分离的粪肠球菌菌株鉴定出VanN型万古霉素耐药性

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Abstract

Five VanN-type vancomycin-resistant Enterococcus faecium strains were isolated from a sample of domestic chicken meat in Japan. All isolates showed low-level resistance to vancomycin (MIC, 12 mg/liter) and had the same pulsed-field gel electrophoresis profile. The vancomycin resistance was encoded on a large plasmid (160 kbp) and was expressed constitutively. The VanN-type resistance operon was identical to the first resistance operon to be reported, with the exception of a 1-bp deletion in vanT(N) and a 1-bp substitution in vanS(N).

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