Abstract
INTRODUCTION: Compartment syndrome is an emergent condition of increased pressure within a muscle compartment. The paraspinal region is a rare location for compartment syndrome and is typically secondary to exertion, trauma, or surgery. CASE REPORT: We present a case of paraspinal compartment syndrome in a patient who presented after fentanyl overdose. This patient was likely exposed to xylazine, also known as "tranq," which may have contributed to his presentation. CONCLUSION: Emergency physicians must be aware of paraspinal compartment syndrome to facilitate rapid diagnosis and treatment and prevent associated morbidity and mortality.