Abstract
With the advent of broad spectrum antibiotics, chronic osteomyelitis of jaw, especially of maxilla, has become a rare lesion. Osteomyelitis of jaw is associated with a complex microbiota, the most common oral microorganism being, Staphylococcus sp. Reported cases of jaw osteomyelitis caused by enteric bacteria are very few in literature. Hereby, we are reporting a case of E.coli associated osteomyelitis in a diabetic individual who had presented with very aggressive bilateral maxillary necrosis. After extensive literature search, to the best of our knowledge, this is the first case of maxillary osteomyelitis associated with E.coli which we have come across.