How multi-component cascades operate in cells: lessons from the ubiquitin system-containing liquid-separated condensates

细胞内多组分级联反应的运作机制:来自含泛素系统的液相分离凝聚体的启示

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Abstract

Membraneless condensates have recently caught the attention of biologists as hubs for cellular components required for catalysis of basic processes. Whether they are real has become the center of heated discussion where the main issues are their mechanism of assembly and function. A recent study describing these condensates as hubs for protein degradation by the ubiquitin system may shed a new light on this recent development in cell biology.

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