Abstract
Sturge-Weber Syndrome (SWS) is a non-familial neurocutaneous disease related to capillary-venous malformations affecting many parts, such as the brain, skin, eyes, face, and respiratory tract and characterized by facial capillary malformation (port wine stain), which is a highly complex and significant challenge for anaesthesiologists. Difficult ventilation and intubation are expected in patients with airway, mouth, lip, and facial involvement of angiomas. Soft induction intubation and extubation are required to prevent increased intracranial (ICP) and intraocular pressure (IOP). We aimed to present the case of a 36-year-old female patient with a hemangioma covering three-quarters of the oral cavity, pharynx, larynx, floor of the mouth, face, neck, and both arms, and her lower lip was significantly swollen and protruding due to the angioma, and she had macroglossia. Therefore, a comprehensive preoperative multidisciplinary approach to examining, evaluating, and closely monitoring these patients is crucial for successful anesthesia management.